Clomid Challenge Test
Clomiphene Citrate Challenge Test (CCCT)
Ovarian Function Study
The clomiphene challenge test is used to assess the ability of the ovaries to respond to hormone signals. This helps with counseling concerning options for future treatment. There is some variability in how different programs request a CCCT. Below is a general guideline of the most common approach.
PATIENT SCHEDULE
Day 1: Onset menses
Day 3: Blood draw
- Serum Estradiol (E2)
- Serum FSH
Day 5-9: Clomid 100mg DAILY (two 50 mg tablets)
Day 10: Blood draw
- Serum FSH
- +/- Serum Estradiol (E2)
- +/- Serum LH
Expected Values
CD (cycle day) 3 |
E2 value 65-70 |
FSH value below 10 |
CD (cycle day) 10 or 11 |
LH value below 10 |
FSH value below 10 |
Women with elevated FSH levels may demonstrate diminished ovarian reserve.
